Diuretics. IV. 6-Chloro-3-substituted 7-Sulfamoyl-1, 2, 4-benzothiadiazine 1, 1-Dioxides

CW Whitehead, JJ TRAVERSO…

Index: Whitehead,C.W. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 2809 - 2813

Full Text: HTML

Citation Number: 7

Abstract

hexylmethyl). The mixed anhydride of trifluoroacetic acid and cyclopentylacetic acid (V. R= cyclopentylmethyl) was prepared by mixing trifluoroacetic anhydride with cyclopentylacetic acid. The crude mixed anhydride reacted with I11 to yield 4-chloro-6- cyclopentylacetylaminobensene-1, 3-disulfonamide. There was no evidence of the other possible product, 4-chloro-6-trifluoroacetylaminobenzene-1, 3-disulfonamide having been ...