Copper (I) Oxide Catalyzed N-Arylation of Azoles and Amines with Arylboronic Acid at Room Temperature under Base-Free Conditions

…, GT Venkanna, KBS Kumar, V Balasubrahmanyam

Index: Sreedhar, Bojja; Venkanna, Gopaladasu T.; Shiva Kumar, Kota Balaji; Balasubrahmanyam, Vura Synthesis, 2008 , # 5 p. 795 - 799

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Citation Number: 37

Abstract

Abstract N-Arylation of azoles and amines with arylboronic acids was efficiently carried out with heterogeneous copper (I) oxide in methanol at room temperature under base-free conditions. The products N-arylazoles and N-arylamines were isolated in good to excellent yields. A variety of arylboronic acids and amines were converted to the corresponding N- arylazoles and N-arylamines, demonstrating the versatality of the reaction.

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