Hydrolysis of amides to carboxylic acids using phthalic anhydride under microwave irradiation and solvent-free conditions

…, D Zargarani, RH Shoar, S Khaleghi

Index: Heravi, Majid M.; Zargarani, Dordaneh; Shoar, Rahim Hekmat; Khaleghi, Shahnaz Journal of Chemical Research, 2005 , # 2 p. 119 - 120

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Abstract

Hydrolysis is an important transformation in organic chemistry and because of its significant role, the development of new reagents and the modification of existing methods are still important. 1 Many reagents are now available for almost every conceivable type of hydrolysis. 2 Since amides are more difficult to hydrolyse than esters chemoselective hydrolysis of them is an attractive objective. Tetrahalophthalic anhydride4 and sodium ...

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