Chemico-biological interactions

Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4

J Dai, F Zhang, J Zheng

Index: Chemico-Biological Interactions, , vol. 183, # 1 p. 49 - 56

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Citation Number: 9

Abstract

... Chemico-Biological Interactions. ... 1). Currently, information regarding the interaction of PAs with cytochromes P450 is limited. ... to control activity at time 0 (Table 2). The percent remaining P450 3A4 activities measured after dialysis were corrected by the volume change due to ...