The triphenyltin (VI) complexes of NSAIDs and derivatives. Synthesis, crystal structure and antiproliferative activity. Potent anticancer agents

V Dokorou, A Primikiri, D Kovala-Demertzi

Index: Dokorou, Vaso; Primikiri, Alexandra; Kovala-Demertzi, Dimitra Journal of Inorganic Biochemistry, 2011 , vol. 105, # 2 p. 195 - 201

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Citation Number: 27

Abstract

The novel triphenyltin (IV) esters of flufenamic acid (1), Hflu,[Ph3Sn (flu)](2), and of [2-(2, 3- dichlorophenylamino) benzoic acid](3), Hdcpa,[Ph3Sn (dcpa)](4) have been structurally characterized by means of vibrational and 1H, 13C NMR spectroscopic studies. The crystal and molecular structures of [SnPh3 (dcpa)(DMSO)] 4a are described. The molecular structure of 4a reveals that the Sn atom has a distorted trigonal bipyramidal coordination ...