Preparation of N-Substituted 1-(p-Hydroxyphenyl)-2-aminoethanols1

JR Corrigan, MJ Langerman…

Index: Corrigan; Langerman; Moore Journal of the American Chemical Society, 1945 , vol. 67, p. 1894

Full Text: HTML

Citation Number: 15

Abstract

In an extensive investigation of highly active broncholytic compounds in the epinephrine series, KonzettU reported that l-(p-hydroxypheny1)-2-isopropylaminoethanol hydrochloride possessed marked activity as a bronchodilator, and that it was more active than the corresponding methyl analog, l-(p-hydroxyphenyl)-2-methylaminoeth-an01 (Synephrine). This observation prompted us to prepare a number of other derivatives in this series for ...