Chemical Communications

Chiral cobalt-catalyzed enantioselective aerobic oxidation of α-hydroxy esters

SK Alamsetti, G Sekar

Index: Alamsetti, Santosh Kumar; Sekar, Govindasamy Chemical Communications, 2010 , vol. 46, # 38 p. 7235 - 7237

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Citation Number: 26

Abstract

A chiral cobalt-catalyzed enantioselective aerobic oxidative kinetic resolution of (±)-α- hydroxy esters, using molecular oxygen as a sole oxidant, is reported and a maximum of selectivity factor (s) 31.9 was achieved with> 99% enantiomeric excess for unreacted α- hydroxy esters.

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