The Thermal Racemization of Dimethyl (-)-Bromosuccinate

LJ Andrews, JE Hardwicke

Index: Andrews; Hardwicke Journal of the American Chemical Society, 1952 , vol. 74, p. 3582,3585

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Citation Number: 6

Abstract

Contrary to a previous report it has been found that no extensive racemization occurs when optically active bromosuccinic acid is converted to its dimethyl ester with diazornethane. The ester does, however, lose activity when subjected to repeated distillation under reduced pressure. To demonstrate the sensitivity of this ester to thermal racemization a series of kinetic measurements of the rate of loss of optical activity of this compound at several ...