Enantioselective polymerization of epoxides: a highly active and selective catalyst for the preparation of stereoregular polyethers and enantiopure epoxides

W Hirahata, RM Thomas, EB Lobkovsky…

Index: Hirahata, Wataru; Thomas, Renee M.; Lobkovsky, Emil B.; Coates, Geoffrey W. Journal of the American Chemical Society, 2008 , vol. 130, # 52 p. 17658 - 17659

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Citation Number: 93

Abstract

A chiral, bimetallic cobalt catalyst was discovered that is highly active and enantioselective for epoxide polymerization. The enantiomerically pure catalyst system exhibits a stereoselectivity factor (s= k fast/k slow) of 370 for propylene oxide, allowing enantiomerically pure epoxide to be recovered in nearly the maximum theoretical yield. In addition, the racemic catalyst forms highly isotactic poly (propylene oxide) in quantitative ...

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