Asymmetric transformation of enones with Synechococcus sp. PCC 7942

K Shimoda, N Kubota, H Hamada, S Yamane…

Index: Shimoda, Kei; Kubota, Naoji; Hamada, Hiroki; Yamane, Shin-Ya; Hirata, Toshifumi Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 12 p. 2269 - 2272

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Citation Number: 16

Abstract

Asymmetric transformation of enones was investigated with cultured cells of Synechococcus sp. PCC 7942 (a cyanobacterium). The cells reduced both the endocyclic C–C double bond of s-trans enones and the exocyclic C–C double bond of s-cis enones with high enantioselectivity to afford optically active α-substituted (S)-ketones under illumination. In addition, the reduction of the double bond of these enones was accompanied by the ...

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