Synthesis and antibacterial activity of a novel series of potent DNA gyrase inhibitors. Pyrazole derivatives

A Tanitame, Y Oyamada, K Ofuji…

Index: Journal of Medicinal Chemistry, , vol. 47, # 14 p. 3693 - 3696

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Citation Number: 232

Abstract

... Journal of Medicinal Chemistry. ... resistant Gram-positive bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and vancomycin-resistant enterococci (VRE), have become a serious medical problem. ...