Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists 1
DJ Sall, AE Arfsten, JA Bastian…
Index: Journal of Medicinal Chemistry, , vol. 40, # 18 p. 2843 - 2857
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Citation Number: 29
Abstract
... Journal of Medicinal Chemistry. ... More recently, the pharmaceutical strategy has focused on the design of small molecule, orally active antagonists for the chronic and/or prophylactic treatment of arterial thrombosis. ...
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[Sall, Daniel J.; Arfsten, Ann E.; Bastian, Jolie A.; Denney, Michael L.; Harms, Cathy S.; McCowan, Jefferson R.; Morin Jr., John M.; Rose, Jack W.; Scarborough, Robert M.; Smyth, Mark S.; Um, Suzane L.; Utterback, Barbara G.; Vasileff, Robert T.; Wikel, James H.; Wyss, Virginia L.; Jakubowski, Joseph A. Journal of Medicinal Chemistry, 1997 , vol. 40, # 18 p. 2843 - 2857]