Tetrahedron Letters

One-pot synthesis of quinoxaline-2-carboxylate derivatives using ionic liquid as reusable reaction media

HM Meshram, P Ramesh, GS Kumar, BC Reddy

Index: Meshram; Ramesh; Santosh Kumar; Chennakesava Reddy Tetrahedron Letters, 2010 , vol. 51, # 33 p. 4313 - 4316

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Citation Number: 40

Abstract

The catalyst-free one-pot synthesis of quinoxaline-2-carboxylate is reported by the reaction of α-halo-β-ketoesters with 1, 2-diamines using an ionic liquid as an environmentally benign solvent. The recovered ionic liquid was reused for four to five cycles. Moreover, the method is applicable for a variety of 1, 2-diamines and α-halo-β-ketoesters.