Synthesis of chiral non-racemic azetidines by lipase-catalysed acetylations and their transformation into amino alcohols: precursors of chiral catalysts
G Guanti, R Riva
Index: Guanti, Giuseppe; Riva, Renata Tetrahedron Asymmetry, 2001 , vol. 12, # 4 p. 605 - 618
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Citation Number: 29
Abstract
Azetidinic mono-acetate 7, diol 6b and di-acetate 10a were prepared with high ee using PPL- catalysed acetylations. The absolute configurations of all new enantioenriched compounds were assigned by chemical correlation with known compounds. Mono-acetate 7 was then transformed into 30, an amino alcohol of noteworthy potential interest since it represents an interesting precursor for chiral catalysts, such as 32.
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