Part 3: Design and synthesis of proline-derived α 2 δ ligands

DJ Rawson, D Brugier, A Harrison, J Hough…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 12 p. 3771 - 3773

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Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Pregabalin (Lyrica®) (1) 1 and 2 has recently been approved for the management of neuropathic pain associated with diabetic peripheral neuropathy and post-herpetic neuralgia and is now a leading medicine in the treatment of ...

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