Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors
S Ozcan, A Kazi, F Marsilio, B Fang…
Index: Journal of Medicinal Chemistry, , vol. 56, # 10 p. 3783 - 3805
Full Text: HTML
Citation Number: 10
Abstract
... Journal of Medicinal Chemistry. ... Chemistry. The screening hit 1 was identified as a CT-L proteasome inhibitor with an IC 50 value of 0.60 ± 0.18 μM (in vitro). Validation of the synthetic route to 1 was undertaken to confirm ...
Related Articles:
Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors
[Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M. Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805]