Virtual Screening and Synthesis of New Chemical Scaffolds as VEGFR-2 Kinase Inhibitors

MS Elsayed, ME El-Araby, RT Serya…

Index: Arzneimittel-Forschung/Drug Research, , vol. 62, # 12 p. 554 - 560

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Abstract

... Arzneimittelforschung 2012; 62(12): 554-560 DOI: 10.1055 ... were prepared according to the ligand preparation protocol of Accelry's Discovery Studio 2.5.5 [12] According to ... Shape or exclusion volume constrains were not added to the pharmacophore in order to keep its scope as ...