Russian Journal of Organic Chemistry

Intramolecular cyclization of N-aryl-3-phenylprop-2-ynamides

DS Ryabukhin, AV Vasil'ev

Index: Ryabukhin; Vasil'ev Russian Journal of Organic Chemistry, 2008 , vol. 44, # 12 p. 1849 - 1851

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Citation Number: 9

Abstract

Heterocyclic quinoline system constitutes the basic structural fragment of many natural and synthetic biologically active substances [1–3]. Therefore, development of new methods for the preparation of quinoline derivatives is an important problem of organic chemistry. A promising procedure for the synthesis of 4-arylquinolin-2 (1H)-ones is based on intramolecular cyclization of N, 3-diarylprop-2-ynamides by the action of acid reagents. ...

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