Tetrahedron

Amberlyst®-15: a reusable heterogeneous catalyst for the dehydration of tertiary alcohols

LMT Frija, CAM Afonso

Index: Frija, Luis M.T.; Afonso, Carlos A.M. Tetrahedron, 2012 , vol. 68, # 36 p. 7414 - 7421

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Citation Number: 9

Abstract

Tertiary alcohols react under mild conditions in the presence of Amberlyst®-15 (dry)(solid- supported sulfonic acid) to give predominantly the most stable alkene in very good yield. The dehydration of tertiary alcohol functionality occurs without observation of rearrangement and polymerization products, and with outstanding substrate tolerance, which include the NHCBz, NHBoc, OSEM, OTBDMS, OBOM and ethylene ketal functional groups. Amberlyst ...

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