Tetrahedron Letters

Unexpected ring-expansion of 1, 2-benzisoxazol-3-ones

SA Raw, AM O'Kearney-McMullan, MA Graham

Index: Raw, Steven A.; O'Kearney-Mcmullan, Anne M.; Graham, Mark A. Tetrahedron Letters, 2011 , vol. 52, # 50 p. 6775 - 6778

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Citation Number: 2

Abstract

A novel and unexpected ring-expansion reaction of 1, 2-benzisoxazol-3-ones is identified. The scope of this reaction is exemplified and the proposed mechanism is also implicated in another degradation process. This reaction also represents a new method for accessing the 4H-1, 3-benzoxazin-4-one skeleton.