Asymmetric Synthesis of Unnatural Amino Acids and Tamsulosin Chiral Intermediate

VR Arava, SR Amasa, BK Goud Bhatthula…

Index: Arava, Veera Reddy; Amasa, Srinivasulu Reddy; Goud Bhatthula, Bharat Kumar; Kompella, Laxmi Srinivas; Matta, Venkata Prasad; Subha Synthetic Communications, 2013 , vol. 43, # 21 p. 2892 - 2897

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Abstract

An efficient and enantioselective hydrogenation of N-acetylamino phenyl acrylic acids was successfully developed by using ruthenium catalyst. This methodology is important in the field of pharmaceuticals and provides a new process for the preparation of unnatural amino acids and tamsulosin chiral intermediate. ... [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full ...

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