Journal of the American Chemical Society

The preparation and dichromate oxidation of certain 6-substituted phenanthridines

H Gilman, J Eisch

Index: Gilman; Eisch Journal of the American Chemical Society, 1957 , vol. 79, p. 4423,4425

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Citation Number: 16

Abstract

The preparation of 6-substituted phenanthridines and their 5, g-dihydro derivatives by the organometallic alkylation of phenanthridine has been examined. It was found that not only do organolithium compounds (n-butyl-and o-tolyllithium) attack phenanthridine readily, but active Grignard reagents such as benzylmagnesium chloride can also add to the azomethine linkage. Finally, even ordinary Grignard reagents such as n- ...