Iodine/Et 3 SiH: a novel reagent system for the synthesis of 3-aryl-1H-indenes from 1, 3-diaryl propargyl alcohols
BVS Reddy, BB Reddy, KVR Rao, JS Yadav
Index: Reddy, B.V. Subba; Reddy, B. Brahma; Rao, K.V. Raghavendra; Yadav Tetrahedron Letters, 2010 , vol. 51, # 43 p. 5697 - 5700
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Citation Number: 10
Abstract
1, 3-Diaryl propargyl alcohols undergo smooth intramolecular Friedel–Crafts cyclization with triethylsilane in the presence of 10mol% iodine 3-aryl-1H-indene derivatives in good yields in short reaction times. This is the first example on the synthesis of substituted indenes from 1, 3-diaryl propargyl alcohols. The use of inexpensive and readily available molecular iodine makes this method quite simple, more convenient, and practical.
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