Tetrahedron letters

One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent

CO Kangani, DE Kelley

Index: Kangani, Cyrous O.; Kelley, David E. Tetrahedron Letters, 2005 , vol. 46, # 51 p. 8917 - 8920

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Citation Number: 41

Abstract

A mild and highly efficient one pot–one step condensation and/or condensation–cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2, 2-dimethyl-1-propanol resulted with excellent yields.