Tetrahedron

One-pot synthesis of fluorine containing 3-cyano/ethoxycarbonyl-2-methyl-benzo [b] furans

…, D Maitraie, S Ravikanth, R Yadla, B Narsaiah, PS Rao

Index: RamaRao; Venkat Reddy; Maitraie; Ravikanth; Yadla; Narsaiah; Shanthan Rao Tetrahedron, 2004 , vol. 60, # 52 p. 12231 - 12237

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Citation Number: 23

Abstract

Fluoro-substituted 3-cyano-2-methyl-benzo [b] furans and ethyl 2-methyl-benzo [b] furan-3- carboxylates are conveniently prepared in a single step in good yield by the microwave induced tandem intramolecular Wittig and Claisen rearrangement reactions of the corresponding [(aryloxyacetyl)(cyano) methylene] triphenylphosphorane and [(aryloxyacetyl)(ethoxycarbonyl) methylene] triphenylphosphoranes, respectively.