Journal of the American Chemical Society

Dialkylacetyl Biurets

AJ Hill, WM Degnan

Index: Hill; Degnan Journal of the American Chemical Society, 1940 , vol. 62, p. 1595

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Citation Number: 22

Abstract

In spite of the considerable success of the hypnotics of the acetamide, acyl urea, and barbituric acid types, a need still exists for less toxic compounds with hypnotic properties. The structural features which appear to account for the pharmacological action of the above- mentioned compounds are two: one or more-CONH-groups, and branched-chain alkyl groups whose function is apparently to confer high lipoid-solubility on the molecules of ...

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