The Cyclization of Arylaminomethyl Styryl Ketones to 1-Aryl-5-phenyl-3-pyrrolidones

PL Southwick, HL Dimond

Index: Southwick; Dimond Journal of the American Chemical Society, 1954 , vol. 76, p. 5667,5670

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Citation Number: 2

Abstract

H HC- C except the p-carbethoxyanilino derivative (X= CO~ C~ H~) and CaH. CHCH2cOCH21 ('~ X CXseH every case, giving yields ranging from 22 to 60% and little or no tar. Simultaneously with cyclization to the 3-pyrrolidones, however, conjugate addition of sodium bisulfite (reaction 2) occurred to give the 8-sulfonates VI. The cyclization most thoroughly studied was However, the observation that cyclization of the that of ...