The Journal of organic chemistry

One-Pot Synthesis of α-Carbolines via Sequential Palladium-Catalyzed Aryl Amination and Intramolecular Arylation

JK Laha, P Petrou, GD Cuny

Index: Laha, Joydev K.; Petrou, Philip; Cuny, Gregory D. Journal of Organic Chemistry, 2009 , vol. 74, # 8 p. 3152 - 3155

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Citation Number: 45

Abstract

A one-pot synthesis of α-carbolines via a palladium-catalyzed aryl amination followed by intramolecular arylation is described. 2, 3-Dichloro-and 2, 3-dibromopyridines have been shown to react with readily available anilines to obtain various substituted α-carbolines in moderate to excellent yields.