Journal of Chemical Research

Synthesis of 3-methyl-6-amino-5-cyano-4-aryl-1-phenyl-1, 4-dihydropyrano [2, 3-c] pyrazole catalysed by KF-montmorillonite

N Wu, X Li, Y Wang, D Shi

Index: Wu, Nan; Li, Xinnian; Wang, Yumei; Shi, Daqing Journal of Chemical Research, 2008 , # 1 p. 16 - 17

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Abstract

The reaction of substituted arylidenemalononitriles and 3-methyl-1-phenyl-2-pyrazolin- 5-one in DMF in the presence of KF-montmorillonite provides a rapid synthesis of 3-methyl-6-amino -5-cyano-4-aryl-1-phenyl-1,4-dihydro- pyrano[2,3-c]pyrazole derivatives. ... Keywords: 1,4-dihydropyrano[2,3-c]pyrazole, KF-montmorillonite, synthesis, 4H-pyran ... 4H-Pyran derivatives are important building blocks for many natural compounds1-4 with anti-allergic5 and anti- ...

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