Tetrahedron letters

1, 2, 3, 4-Tetrahydro-1-naphthyl ester as a selective protecting group for carboxylic acids

CJ Slade, CA Pringle, IG Sumner

Index: Slade, Christopher J.; Pringle, Carol A.; Sumner, Ian G. Tetrahedron Letters, 1999 , vol. 40, # 30 p. 5601 - 5604

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Citation Number: 2

Abstract

The carboxylic acid functionality can be protected as the 1, 2, 3, 4-tetrahydro-1-naphthyl ester, which can be selectively cleaved in the presence of aryl and alkyl esters using chlorotrimethylsilane and sodium iodide in acetonitrile. This protecting group allows room ...