Utilization of Alkoxy Ketones in the Synthesis of Quinolines by the Pfitzinger Reaction. II1

SD Lesesne, HR Henze

Index: Lesesne; Henze Journal of the American Chemical Society, 1942 , vol. 64, p. 1897,1898

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Citation Number: 20

Abstract

It has been shown recently in this Laboratory phorus, I was converted into 2-ethyl-1, 2, 3, 4- tetrathat keto ethers4 can be employed in the syn-hydro-3-methylquinoline (V). In turn, V, by acthesis of quinoline derivatives by the Pfitzinger tion of hydrochloric acid and tin, yielded 1, 2, 3, 4-reaction. Thus, 4b ethoxyacetone and ethoxy-tetrahydro-3-methylquinoline (VI). 6 Reduction methyl ethyl ketone, respectively, were condensed without cleavage was ...