Steroidal sapogenins. I. Transformation of kryptogenin into diosgenin and pseudodiosgenin

S Kaufmann, G Rosenkranz

Index: Kaufmann; Rosenkranz Journal of the American Chemical Society, 1948 , vol. 70, p. 3502,3504

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Citation Number: 9

Abstract

Summary Mandelic acid, labelled C14 in the a-position, was obtained from similarly labelled phenylglyoxal on treatment with alkali, thus demonstrating that no rearrangement of the carbon skeleton occurs and consequently that the reaction proceeds by a shift of the aldehydic hydrogen atom. The similar reaction of a, a-dibromoacetophenone with aqueous alkali has also been shown to occur without rearrangement.