Synthesis of cationic metalloporphyrin precursors related to the design of DNA cleavers

C Casas, B Saint-Jalmes, C Loup…

Index: Casas, Christiane; Saint-Jalmes, Bernadette; Loup, Christophe; Lacey, C. Jeffrey; Meunier, Bernard Journal of Organic Chemistry, 1993 , vol. 58, # 10 p. 2913 - 2917

Full Text: HTML

Citation Number: 61

Abstract

The design of specific DNA cleavers is a growing field of research for several reasons:(i) DNA is the biological target of a large number of antitumor agents which are able to cleave double-stranded nucleic acids, bleomycin,'neocarzinostatin, 2 and enediyne molecules, 3 (ii) transition metal complexes linked to a DNA recognizing molecule (intercalating agentst peptides: or oligonucleotides6) are also able to cleave selectively single-or double- ...

Related Articles:

Design and synthesis of conformationally restricted inhibitors of active thrombin activatable fibrinolysis inhibitor (TAFIa)

[Brink, Mikael; Dahlen, Anders; Olsson, Thomas; Polla, Magnus; Svensson, Tor Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2261 - 2268]

Efficient synthesis of azetidine through N??trityl??or N??dimethoxytritylazetidines starting from 3??amino??l??propanol or 3??halopropylamine hydrohalides

[Huszthy; Bradshaw; Krakowiak; Wang; Dalley Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1197 - 1207]

Efficient synthesis of azetidine through N??trityl??or N??dimethoxytritylazetidines starting from 3??amino??l??propanol or 3??halopropylamine hydrohalides

[Huszthy; Bradshaw; Krakowiak; Wang; Dalley Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1197 - 1207]

Anti-MRSA cephems. Part 2: C-7 cinnamic acid derivatives

[Springer, Dane M.; Luh, Bing-Yu; Goodrich, Jason; Bronson, Joanne J. Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 2 p. 265 - 279]

Efficient synthesis of azetidine through N??trityl??or N??dimethoxytritylazetidines starting from 3??amino??l??propanol or 3??halopropylamine hydrohalides

[Huszthy; Bradshaw; Krakowiak; Wang; Dalley Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 5 p. 1197 - 1207]

More Articles...