Tetrahedron

Regioselective ortho-nitration of N-phenyl carboxamides and primary anilines using bismuth nitrate/acetic anhydride

Y Lu, Y Li, R Zhang, K Jin, C Duan

Index: Lu, Yang; Li, Yaming; Zhang, Rong; Jin, Kun; Duan, Chunying Tetrahedron, 2013 , vol. 69, # 45 p. 9422 - 9427

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Citation Number: 10

Abstract

Abstract An efficient and one-pot synthetic method for the regioselective ortho-nitration of the N-phenyl carboxamides and primary anilines has been developed by using bismuth nitrate and acetic anhydride as the nitrating reagents. Reaction proceeds at room temperature and results in corresponding ortho-nitrated products in moderate to excellent yields. This method provides an operationally simple, regioselective, and efficient access to synthesize o-nitro ...

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