Journal of the American Chemical Society

Studies in the Phenanthrene Series. VII. 3-Hydroxyacetylphenanthrenes and Amino Ketones and Alcohols Derived from Them. Hydroxyaminophenanthrenes1

A Burger, E Mosettig

Index: Burger; Mosettig Journal of the American Chemical Society, 1934 , vol. 56, p. 1745

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Citation Number: 3

Abstract

Some of the phenanthrene derivatives which contain the pharmacologically interesting hydroxyethylamino side chain,-CHOH-CH2-NR2 (RH or produce in the cat a typical morphine-like excitement, dilatation of the pupils and marked analge~ ia.~ Since there is but little doubt that the phenolic hydroxyl group in position 3 in morphine plays an essential role in the physiological action of this alkaloid, it seemed necessary to follow the change in the ...