Archiv der Pharmazie

New Cyanopeptide??Derived Low MolecularWeight Thrombin Inhibitors

G Radau, J Gebel, D Rauh

Index: Radau, Gregor; Gebel, Jana; Rauh, Daniel Archiv der Pharmazie, 2003 , vol. 336, # 8 p. 372 - 380

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Citation Number: 19

Abstract

Abstract Thrombosis is the result of defective regulation of the hemostasis system. This cardiovascular disorder may lead to deep vein thrombosis, myocardial infarction, and stroke. The majority of current drug research is focused on finding inhibitors of thrombin—the global player in hemostasis. In our work, we emphasize investigation of the marine environment to yield new lead structures from marine organisms like blue-green algae (cyanobacteria). ...

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