Rational design of an indolebutanoic acid derivative as a novel aldose reductase inhibitor based on docking and 3D QSAR studies of phenethylamine derivatives

WS Sun, YS Park, J Yoo, KD Park, SH Kim…

Index: Kotani, Takayuki; Nagaki, Yasuhiro; Ishii, Akira; Konishi, Yukari; Yago, Hisashi; Suehiro, Seishi; Okukado, Nobuhisa; Okamoto, Kaoru Journal of Medicinal Chemistry, 1997 , vol. 40, # 5 p. 684 - 694

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Citation Number: 28

Abstract

... Journal of Medicinal ... with progress in computer technology, a significant advance has been made in the application of computer modeling to medicinal chemistry. ... discovered a series of indole-3-acetic acids analogues as ARIs by screening the 3D chemical database (ACD3D). ...