Parallel solution-and solid-phase synthesis of spiropyrrolo-pyrroles as novel neurokinin receptor ligands

KH Bleicher, Y Wüthrich, G Adam, T Hoffmann…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 21 p. 3073 - 3076

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Citation Number: 31

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 4. Since spiropiperidines are considered as pharmacologically relevant molecules for various targets within the area of G-protein coupled receptors, this class of chemical motives is often referred to as 'privileged GPCR-structures'. ...