Kinetic resolution of aromatic β-amino acids by ω-transaminase

HS Bea, HJ Park, SH Lee, H Yun

Index: Bea, Han-Seop; Park, Hye-Jeong; Lee, Sang-Hyeup; Yun, Hyungdon Chemical Communications, 2011 , vol. 47, # 20 p. 5894 - 5896

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Citation Number: 36

Abstract

TAs have been studied for the production of chiral amino acids because they generally show rapid reaction rates, broad substrate specificity, and high enantioselectivity. 10 Generally TAs can be classified into α-TAs and ω-TAs according to the relative position of the amino group that is to be transferred with respect to the carboxyl group of the substrate. ω-TAs are defined as enzymes that transfer an amino group from an amino donor onto a carbonyl moiety of an amino ...