Synthesis and evaluation of 1-(arylsulfonyl)-2-[(methoxycarbonyl) sulfenyl]-1-methylhydrazines as antineoplastic agents

…, K Shyam, LA Cosby, AC Sartorelli

Index: Hrubiec; Shyam; Cosby; Sartorelli Journal of Medicinal Chemistry, 1986 , vol. 29, # 9 p. 1777 - 1779

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Abstract

Robert T. Hrubiec, Krishnamurthy Shyam, Lucille A. Cosby, and Alan C. Sartorelli* ... Department of Pharmacology and Developmental Therapeutics Program, Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06510. Received September 27, 1985 ... This laboratory has recently described the synthesis of a variety of 1,2-bis(arylsulfonyl )-l-methylhydrazines (1) and have demonstrated their antineoplastic activity against the ...