Novel approach to lactams via (triisopropylsilyl) azidohydrin formation and photoinduced Schmidt rearrangement
PA Evans, DP Modi
Index: Evans, P. Andrew; Modi, Dilip P. Journal of Organic Chemistry, 1995 , vol. 60, # 21 p. 6662 - 6663
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Citation Number: 21
Abstract
Lactams are particularly important molecules owing to their versatility as synthetic intermediates and widespread occurrence in biologically important compounds. lv2 They have also proven extremely informative as transition state models in amide reactivity~ tudies.~ Despite the development of a variety of new methods, 4s5 the Schmidt6 and Beckmann7 reactions remain the most convenient and general protocols for their ...
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