Identification and specificity studies of small-molecule ligands for SH3 protein domains

SR Inglis, C Stojkoski, KM Branson…

Index: Desos, Patrice; Schlewer, Gilbert; Wermuth, Camille Georges Heterocycles, 1989 , vol. 28, # 2 p. 1085 - 1099

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Citation Number: 62

Abstract

... Volume: Page: ... Tec Kinase SH3 domain as a model system for structure-based ligand design, we have identified several simple heterocyclic compounds that ... 1,2 More than 400 examples of the SH3 sequence motif are encoded in the human genome with many ...