Microbial transformation of androst-4-ene-3, 17-dione by Beauveria bassiana
Z Xiong, Q Wei, H Chen, S Chen, W Xu, G Qiu, S Liang…
Index: Xiong, Zhigang; Wei, Qi; Chen, Hanmei; Chen, Shouwen; Xu, Wenjin; Qiu, Guofu; Liang, Shucai; Hu, Xianming Steroids, 2006 , vol. 71, # 11-12 p. 979 - 983
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Citation Number: 34
Abstract
The microbial transformation of androst-4-ene-3, 17-dione (I) by the fungus Beauveria bassiana CCTCC AF206001 has been investigated using pH 6.0 and 7.0 media. Two hydroxylated metabolites were obtained with the pH 6.0 medium. The major product was 11α-hydroxyandrost-4-ene-3, 17-dione (II) whereas the minor product was 6β, 11α- dihydroxyandrost-4-ene-3, 17-dione (III). On the other hand, four hydroxylated and/or ...
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