Tetrahedron

Tin tetrachloride-induced π-cyclizations of glycine cation equivalents to substituted pipecolic acid derivatives

…, IM Boska, H Hiemstra, RF de Boer, WN Speckamp

Index: Esch, Peter M.; Boska, Ilona M.; Hiemstra, Henk; Boer, Richard F. de; Speckamp, W. Nico Tetrahedron, 1991 , vol. 47, # 24 p. 4039 - 4062

Full Text: HTML

Citation Number: 46

Abstract

Cationic π-cyclization reactions of N-(3-alkenyl)-N-(methoxycarbonyl) acetoxyglycine esters induced by tin tetrachloride in dichloromethane are described. Reactions started and quenched with water at-78° C mainly yield cis-4-hydroxypipecolic esters, whereas ...