The Reactions of Dibromoalkanes and o-(Bromoalkyl)-α-bromotoluenes with o-Substituted Anilines. The Synthesis of 1-Arylpyrrolidines and Related Compounds
AH Sommers
Index: Sommers Journal of the American Chemical Society, 1956 , vol. 78, p. 2439,2445
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Citation Number: 14
Abstract
The reaction of 1, 4-dibromoalkanes with o-substituted and o, o'-disubstituted anilines yielded only 1-arylpyrrolidines except in one case when a low yield of the substituted l, 4- diaminoalkane was obtained. Similarly, 2-(P-bromoethyl'i-abromotoluene gave only 2-aryl-1, 2, 3, 4-tetrahydroisoquinolines, while a, a'-dibromo-o-xylene gave principally 2- arylisoindolines together with small amounts of substituted a, a'-diamino-o-xylenes. 1, 3- ...
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