Synthesis of dopamine and serotonin derivatives for immobilization on a solid support
…, T Tørring, ALB Kodal, AR Azcargorta…
Index: Funder, Erik Daa; Jensen, Anne Bjornskov; Torring, Thomas; Kodal, Anne Louise Bank; Azcargorta, Ane Rebolledo; Gothelf, Kurt Vesterager Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3134 - 3142
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Citation Number: 4
Abstract
The two important neurotransmitters dopamine and serotonin are synthesized with short PEG tethers and immobilized on a magnetic solid support. The tether is attached to the aromatic moiety of the neurotransmitters to conserve their original functional groups. This approach causes minimal alteration of the original structure with the aim of optimizing the immobilized neurotransmitters for aptamer selection by SELEX. For the dopamine ...
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