Total synthesis of racemic triptolide and triptonide

CK Lai, RS Buckanin, SJ Chen…

Index: Buckanin, Richard S.; Chen, Samuel J.; Frieze, Donna M.; Sher, Frank T.; Berchtold, Glenn A. Journal of the American Chemical Society, 1980 , vol. 102, # 3 p. 1200 - 1201

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Citation Number: 33

Abstract

Tripterygium wilfordii by Kupchan and co-workers.'More recently the isolation of 1 and 3 has been reported by a Chinese group,* and Kutney and co-workers have reported a procedure for preparation of 2 from a tissue culture of T. wilfo~ dii.~ Structural data from X-ray crystallographic studies and from spectroscopic studies clearly indicate, as can be seen from molecular models, that the C-14/3-hydroxyl group of 1 and 2 is hydrogen bonded to the C- ...