Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate—caged SPP
L Qiao, AP Kozikowski, A Olivera, S Spiegel
Index: Qiao, Lixin; Kozikowski, Alan P.; Olivera, Ana; Spiegel, Sarah Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 7 p. 711 - 714
Full Text: HTML
Citation Number: 38
Abstract
The synthesis of a photolyzable sphingosine 1-phosphate derivative is reported via the reaction of N-(tert-butoxycarbonyl)-2-N, 3-O-isopropylidenesphingosine7 and bis (α-methyl- o-nitrobenzyl) N, N-diisopropyl-phosphoramidite. Stimulation of DNA synthesis upon illumination of caged SPP-loaded cells is also described.
Related Articles:
[Walker, Jeffery W.; Reid, Gordon P.; McCray, James A.; Trentham, David R. Journal of the American Chemical Society, 1988 , vol. 110, # 21 p. 7170 - 7177]
[Walker, Jeffery W.; Reid, Gordon P.; McCray, James A.; Trentham, David R. Journal of the American Chemical Society, 1988 , vol. 110, # 21 p. 7170 - 7177]
[Walker, Jeffery W.; Reid, Gordon P.; McCray, James A.; Trentham, David R. Journal of the American Chemical Society, 1988 , vol. 110, # 21 p. 7170 - 7177]
[Walker, Jeffery W.; Reid, Gordon P.; McCray, James A.; Trentham, David R. Journal of the American Chemical Society, 1988 , vol. 110, # 21 p. 7170 - 7177]
[Walker, Jeffery W.; Reid, Gordon P.; McCray, James A.; Trentham, David R. Journal of the American Chemical Society, 1988 , vol. 110, # 21 p. 7170 - 7177]