A photoactivated precipiton for reagent sequestration in solution-phase synthesis
T Bosanac, CS Wilcox
Index: Bosanac, Todd; Wilcox, Craig S. Journal of the American Chemical Society, 2002 , vol. 124, # 16 p. 4194 - 4195
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Citation Number: 31
Abstract
Precipitons are molecular phase tags for chemical separations. They can be switched from a high-solubility to a low-solubility state to facilitate product, reagent, or catalyst isolation. This paper presents the first photoactivated precipiton and demonstrates that this precipiton is an efficient amine scavenging agent in solution-phase syntheses of amides, ureas, and imines. This approach to amine scavenging offers advantages over solid-phase scavenging ...
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