New route for the synthesis of 3-deoxyaldos-2-uloses

H El Khadem, D Horton, MH Meshreki…

Index: El Khadem,H. et al. Carbohydrate Research, 1971 , vol. 17, p. 183 - 192

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Citation Number: 52

Abstract

Abstract 3-Deoxy-D-erythro-and 3-deoxy-D-threo-hexos-2-uloses, 3-deoxy-D-glycero- pentos-2-ulose, and 4-hydroxy-2-oxobutyraldehyde (“3-deoxytetros-2-ulose”) were obtained in about 20% net yields by heating aqueous solutions of D-glucose, D-galactose, D-xylose, and D-erythrose, respectively, with benzoylhydrazine and p-toluidine and decomposing the resultant 3-deoxyaldos-2-ulose bis (benzoylhydrazones) with benzaldehyde. Several 3- ...